EAJAIC
Eurasian Journal of Anesthesiology and Intensive Care

The Eurasian Journal of Anesthesiology and Intensive Care (EAJAIC) is an independent-unbiased, peer-reviewed, "double-blind", and open-access journal of current national and international issues and reviews for original clinical and experimental research, interesting case reports, differential diagnoses, editorial opinions, letters to the editor, and educational papers in anesthesiology, algology, and intensive care medicine.

ISSN: Active
eISSN: 3023-6738
Creative Commons CC BY-NC-ND 4.0 International License.
EndNote Style

Online Manuscript System

Index
Original Article
Retrospective investigation of cases diagnosed with brain death
Abstract
Aims: Early and rapid detection of brain death in intensive care units is important for organ transplantation. This study aimed to evaluate cases diagnosed with brain death.
Methods: The retrospective study was conducted by examining the patients diagnosed with brain death in intensive care units of the city hospital between 06.10.2023 and 01.09.2024. Demographic characteristics of the cases, hospitalization diagnoses, clinics where they received treatment, the time from admission to intensive care and the beginning of clinical suspicion of brain death until the report was prepared, additional tests applied, family organ donation rate, donor rate, and the time from the diagnosis of brain death to cardiac arrest in non-donor cases were recorded.
Results: 33 patients were diagnosed with brain death. The mean age of the cases was 52.1 and 51.6% of them were male (n=17). 57.6% of the cases had no known comorbid diseases (n=19). The intensive care units where the cases were hospitalized were 36.4% anesthesia (n=12), 36.4% neurosurgery(n=12). The hospitalization diagnosis of the cases was intracranial hemorrhage in 30.4% (n=10), cerebral infarction in 30.4%(n=10). Digital Subtraction Angiography was used in 70% (n=23) for additional supporting tests. Organ donation was made by the family in 12.1% of the cases(n=4), and organs were transplanted in 9% of these cases(n=3). The average time from admission to diagnosis of brain death was 6.66 days. The average time from follow-up of patients thought to have brain death to diagnosis of brain death was 2.03 days. The average time from diagnosis of brain death to cardiac arrest was 31.85 hours (
Conclusion: It is very important to diagnose brain death in order to increase the number of organ transplants from cadavers. In patients who may be potential donors, brain death should be determined quickly, and rapid action should be taken after diagnosis and unnecessary loss of time should be avoided.

Keywords : Brain death, intensive care unit, transplantation

Download Article


1. Arsava EM, Demirkaya S, Dora B, et al. Türk nöroloji derneği beyin ölümü tanı kılavuzu. Türk Nöroloji Derg. 2014;20(3):101-104.
2. Mollaret P, Goulon M. Le coma depassé. Rev Neurol. 1959;101:3-15.
3. Alderete JF, Jeri FR, Richardson EP Jr, Sament S, Schwab RS, Young RR. Irreversible coma: a clinical, electroencephalographic and neuropathological study. Trans Am Neurol Assoc. 1968;93:16-20.
4. Organ ve doku alınması, saklanması, aşılanması ve nakli hakkında kanun. Kanun numarası 6514 Resmî Gazete 18.01.2014-28886. https://www.resmigazete.gov.tr/eskiler/2014/01/20140118-1.htm. Erişim tarihi 30Eylül 2024.
5. https://www.uptodate.com/contents/diagnosis-of-brain-death Erişim tarihi: 30Eylül 2024.
6. Palabıyık O. Beyin ölümü tanısı alan hastaların retrospektif analizi. Online Turkish J Health Sci. 2020;5(4):631-640. doi:10.26453/otjhs.806855
7. Kuşçu ÖÖ, Aktay M. Beyin ölümü olgularının retrospektif değerlendirilmesi. Anest Derg. 2021;29(2):99-104. doi:10.5222/jarss.2021.02997
8. Seifi A, Lacci JV, Godoy DA. Incidence of brain death in the United States. Clin Neurol Neurosurg. 2020;195:105885. doi:10.1016/j.clineuro.2020. 105885
9. Eira CSLD, Barros MIT, Albuquerque AMP. Organ donation: the reality of an intensive care unit in Portugal. Doação de órgãos: a realidade de uma unidade de cuidados intensivos portuguesa.Rev Bras Ter Intensiva. 2018; 30(2):201-207. doi:10.5935/0103-507X.20180040
10. Karasu D, Yilmaz C, Karaduman İ, Pekel NB. Beyin ölümü olgularının retrospektif analizi. J Crit Intensive Care. 2015;6(2):23. doi:10.5152/dcbybd. 2015.595
11. Escudero D, Valentín M O, Escalante JL, et al. Intensive care practices in brain death diagnosis and organ donation. Anaesthesia. 2015;70(10):1130-1139. doi:10.1111/anae.13065
12. Karan E, Elgin E, Oflaz R, et al. Bir Üniversite Hastanesi’nde beyin ölümü tanısı konan olgularda organ bağışı oranlarının retrospektif analizi. Uludağ Üni. Tıp Fak Derg. 2019;45(1):41-46. doi:10.32708/uutfd.461923
13. Akbaş T, Kurtpınar Z, Şenadım S, et al. Nöroloji yoğun bakım ünitesinde beyin ölümü tanısı konulan olguların incelenmesi. ACU Sağlık Bil Derg. 2018;9(3):309-313. doi:10.31067/0.2018.30
14. Uzuntarla Y. Retrospective investigation of brain death and organ donation cases in a training and research hospital. GKDA Derg. 2019;25(4):264-269. doi:10.5222/GKDAD.2019.98159
15. Avcı O, Gündoğdu O. Retrospective analysis of the patients with brain death diagnosis in the last five years in our hospital. Cumhuriyet Med J. 2019;41(2):385-391. doi:10.7197/223.vi.574315
16. Citerio G, Murphy PG. Brain death: the European perspective.Semin Neurol. 2015;35(2):139-144. doi:10.1055/s-0035-1547533
17. Sahin M, Altinay M, Cinar AS, Yavuz H. Retrospective analysis of patients diagnosed with brain death in our hospital in the last 15 years.Sisli Etfal Hastan Tip Bul. 2023;57(4):526-530. doi:10.14744/SEMB.2023.65928
18. Sipahioglu H, Elay G, Bingol N, Bahar I. Retrospective analysis of 1998 patients diagnosed with brain death between 2011 and 2019 in Turkey. J Neuroanaesthesiol Crit Care. 2022;9(2):106-111. doi:10.1055/s-0042- 1750093
19. Kıraklı C, Uçar ZZ, Anıl AB, Özbek İ. The effect of shortening confirmed brain death diagnosis time on organ donation rates in the intensive care unit. Yoğun Bakım Derg. 2011;1:8-11. doi:10.5152/dcbybd.2011.02
20. Çakır E, Kocabeyoğlu GM, Gürbüz Ö, BÖ Sevil, Mutlu NM, Işıl ÖT. Yoğun bakım ünitesinde mortalite sıklığı ve risk faktörlerinin değerlendirilmesi. Ankara Eğt Arş Hast Derg. 2020;53(1):20-24. doi:10.20492/aeahtd.537879
Article available in :
Volume 2, Issue 1, 2025
Page : 24-28
https://doi.org/10.51271/EAJAIC-0025
Article Information
Received : 08 Kas 2024
Accepted : 30 Ara 2024
Published : 03 Şub 2025
Corresponding Author :

Sinem Bayrakçı: Gaziantep City Hospital

[email protected]
Citation : Bayrakçı S, Eygi E. Retrospective investigation of cases diagnosed with brain death. Eur J Anesthesiol Intens Care. 2025;2(1):24-28.

Read: 244
Download : 836
Cited: 0
_Footer